Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29371149 | 0.90 | ALDH1A1 (0.40) | ALDH1A1TSHRCETPMAPTHPGD | |
| SCHEMBL472178 | 0.88 | ALDH1A1 (0.38) | ALDH1A1TSHRCETPMAPTHPGD | |
| SCHEMBL20162506 | 0.88 | ALDH1A1 (0.38) | ALDH1A1TSHRCETPMAPTHPGD | |
| SCHEMBL7208532 | 0.84 | LAP3 (0.38) | ALDH1A1TSHRLAP3 | |
| SCHEMBL6553514 | 0.83 | LAP3 (0.36) | ALDH1A1LMNAKDM4ELAP3 | |
| SCHEMBL29794309 | 0.82 | POLB (0.43) | ALDH1A1TSHRMAPTHPGDKDM4E | |
| SCHEMBL7212934 | 0.82 | KDM4E (0.38) | ALDH1A1LMNAL3MBTL1KDM4ELAP3 | |
| SCHEMBL20162498 | 0.81 | POLB (0.42) | ALDH1A1MAPTHPGDKDM4E | |
| Phosphoric Acid SCHEMBL28251406 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRCETPMAPTHPGD | |
| SCHEMBL8846449 | 0.80 | LTA4H (0.44) | ALDH1A1TSHRMAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235833-B1 | ANALOGS OF (1S, CIS)-4-(2-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL | GLAXO GROUP LTD (GB) | 2004-02-25 | — | — | EP | claimed |
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |