Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.39 |
| ▸ | ANPEP | P15144 | 3/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553506 | 0.88 | LAP3 (0.47) | LAP3ANPEPERAP2MEN1KMT2A | |
| SCHEMBL7208532 | 0.84 | LAP3 (0.38) | LAP3ANPEPTSHRSRRACP3 | |
| SCHEMBL7208497 | 0.83 | LAP3 (0.37) | LAP3ANPEPERAP2SRRACP3 | |
| SCHEMBL7212934 | 0.82 | KDM4E (0.38) | LAP3ANPEPMEN1KMT2AKDM4E | |
| SCHEMBL6555636 | 0.76 | ALDH1A1 (0.38) | LAP3TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL7114956 | 0.76 | LAP3 (0.44) | LAP3ANPEPACP3CTRB1ALDH1A1 | |
| SCHEMBL6553514 | 0.73 | LAP3 (0.36) | LAP3ANPEPMEN1KMT2AACP3 | |
| SCHEMBL29761129 | 0.72 | ALPI (0.56) | LAP3ANPEPERAP2SRRACP3 | |
| SCHEMBL4748270 | 0.72 | ALPI (0.56) | LAP3ANPEPERAP2SRRACP3 | |
| SCHEMBL31343122 | 0.71 | KDM4E (0.40) | MEN1KMT2ATSHRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | claimed |