Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18446 | 0.87 | ALDH1A1 (0.53) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL16811766 | 0.80 | ALDH1A1 (0.50) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL6824967 | 0.78 | ALDH1A1 (0.48) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL1857628 | 0.78 | ALDH1A1 (0.43) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL2945943 | 0.78 | GAA (0.46) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL17053029 | 0.78 | — | — | |
| SCHEMBL2948744 | 0.77 | ALDH1A1 (0.48) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL16811720 | 0.76 | ALDH1A1 (0.46) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL16811738 | 0.76 | ALDH1A1 (0.46) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL2941847 | 0.76 | ALDH1A1 (0.46) | ALOX15ALDH1A1LMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874846-B1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2003-04-02 | — | — | EP | claimed |