Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDH1 | P40925 | 3/20 | 0.51 |
| ▸ | MDH2 | P40926 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15467807 | 0.85 | MDH1 (0.60) | MDH1MDH2HIF1AEPAS1MLYCD | |
| SCHEMBL7208905 | 0.84 | NPSR1 (0.55) | MDH1MDH2HIF1AEPAS1TRPV1 | |
| SCHEMBL6332042 | 0.81 | LMNA (0.58) | MLYCDHPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL31303632 | 0.78 | HIF1A (0.81) | MDH1MDH2HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL2957387 | 0.78 | HIF1A (0.81) | MDH1MDH2HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL5263982 | 0.74 | KMT2A (0.58) | HPGDSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL1419452 | 0.74 | HPGD (0.58) | HPGDSMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL359542 | 0.72 | GAA (0.54) | HPGDSMN1; SMN2MAPTALDH1A1MAPK1 | |
| SCHEMBL11088061 | 0.71 | RAB9A (0.58) | HPGDSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL31503974 | 0.71 | TRPV1 (0.70) | MDH1MDH2HIF1AEPAS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755394-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028399-A1 | A METHOD OF INDUCING CHOLECYSTOKININ AGONIST ACTIVITY USING 1,4-BENZODIAZEPINE COMPOUNDS | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |