Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 12/20 | 0.33 |
| ▸ | CA2 | P00918 | 12/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149469 | 0.84 | P2RY6 (0.42) | HSD17B10P2RY6CA1CA2CA12 | |
| SCHEMBL1230833 | 0.82 | HSD17B10 (0.39) | HSD17B10P2RY6CA1CA2CA12 | |
| SCHEMBL6574053 | 0.75 | OPRD1 (0.33) | HSD17B10P2RY6OPRD1 | |
| SCHEMBL7516431 | 0.74 | CA1 (0.59) | HSD17B10P2RY6CA1CA2CA12 | |
| SCHEMBL9278053 | 0.72 | P2RY6 (0.52) | HSD17B10P2RY6CA1CA2OPRD1 | |
| SCHEMBL7205496 | 0.71 | P2RY6 (0.53) | HSD17B10P2RY6CA1CA2CA12 | |
| SCHEMBL7202500 | 0.71 | HSD17B10 (0.46) | HSD17B10P2RY6CA1CA2CA12 | |
| SCHEMBL9408605 | 0.71 | RHOC (0.39) | KDM4E | |
| SCHEMBL16868557 | 0.71 | TDP1 (0.41) | HSD17B10KDM4E | |
| Edetic Acid SCHEMBL5162768 | 0.69 | MIF (0.57) | HSD17B10P2RY6CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057022-B1 | ASSAY FOR SPECIFIC STRAINS OF MULTIPLE DISEASE RELATED CONFORMATIONS OF A PROTEIN | UNIV CALIFORNIA (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1238285-A1 | STEROID COMPOUNDS FOR STEROID RECEPTOR BINDING ASSAYS | Akzo Nobel N.V. (NL) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001040805-A1 | STEROID COMPOUNDS FOR STEROID RECEPTOR BINDING ASSAYS | AKZO NOBEL N.V. (NL) | 2001-06-07 | — | — | WO | disclosed |