Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576787 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNATP53SMN1; SMN2ALOX5 | |
| SCHEMBL27274107 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNATP53SMN1; SMN2ALOX5 | |
| SCHEMBL27396728 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNATP53SMN1; SMN2ALOX5 | |
| SCHEMBL29894083 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL2342911 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL4607473 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL9167218 | 0.81 | F2 (0.43) | ALDH1A1LMNATP53SMN1; SMN2ALOX5 | |
| SCHEMBL4607464 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL11249889 | 0.79 | LMNA (0.49) | ALDH1A1LMNATP53SMN1; SMN2MLYCD | |
| SCHEMBL1061794 | 0.79 | LMNA (0.49) | ALDH1A1LMNATP53SMN1; SMN2MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846682-B9 | PENICILLAMINAMIDE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-05-14 | — | — | EP | disclosed |
| EP-0846682-B1 | PENICILLAMINAMIDE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2002-10-16 | — | — | EP | disclosed |
| US-6239150-B1 | POTENT INHIBITORY ACTIVITY AGAINST THROMBIN, AND ARE USEFUL AS ANTICOAGULANTS. | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0846682-A1 | PENICILLAMINAMIDE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-06-10 | — | — | EP | disclosed |