Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93424 | 0.73 | AHR (0.38) | TLR4 | |
| SCHEMBL9114885 | 0.69 | KMT2A (0.39) | — | |
| SCHEMBL15682041 | 0.65 | MAPT (0.37) | — | |
| SCHEMBL28027609 | 0.64 | CA9 (0.36) | — | |
| SCHEMBL7774767 | 0.62 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL11703412 | 0.62 | MYB (0.39) | — | |
| SCHEMBL9393907 | 0.62 | MCHR1 (0.46) | — | |
| SCHEMBL15682059 | 0.61 | CTSS (0.44) | — | |
| SCHEMBL15682094 | 0.61 | ALDH1A1 (0.35) | — | |
| SCHEMBL28455131 | 0.60 | CTRC (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942899-B1 | MANUFACTURING PROCESS OF METOPROLOL | ASTRAZENECA AB (SE) | 2003-03-12 | — | — | EP | disclosed |
| CN-1332844-A | Reaction monitoring | ASTRAZENECA AB (SE) | 2002-01-23 | — | — | CN | disclosed |
| US-6252113-B1 | O-ETHERIFICATION OF P-(2-METHOXYETHYL)-PHENOL WITH AQUEOUS EPICHLOROHYDRIN, EVAPORATION OF EXCESS EPICHLOROHYDRIN, DISTILLATION, THEN AMINATION WITH ISOPROPYLAMINE TO YIELD METOPROLOL PRODUCT | ASTRAZENECA AB (SE) | 2001-06-26 | — | — | US | disclosed |
| EP-0942899-A1 | MANUFACTURING PROCESS OF METOPROLOL | Astra Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022426-A1 | NEW MANUFACTURING PROCESS OF METOPROLOL | ASTRA AKTIEBOLAG (SE) | 1998-05-28 | — | — | WO | disclosed |