Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10331160 | 0.92 | TSHR (0.46) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL20462801 | 0.90 | TSHR (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL15293384 | 0.90 | MEN1 (0.45) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL1104611 | 0.87 | — | — | |
| SCHEMBL18276 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL10331153 | 0.84 | TSHR (0.48) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL13330247 | 0.84 | MEN1 (0.35) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL5052016 | 0.83 | TSHR (0.37) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL2406752 | 0.83 | TSHR (0.50) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL2624951 | 0.82 | TSHR (0.42) | TSHRMEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933376-B1 | Silanyl-triazines as light screening compositions | HOFFMANN LA ROCHE (CH) | 2003-08-20 | — | — | EP | disclosed |
| US-6018044-A | TRIS((ALKYL, SILANE, OLIGOSILOXANE OR POLYSILOXANE)(OXY OR AMINO)CARBONYL-(1,4-PHENYLENE)-AMINO)-S-TRIAZINES HAVING AT LEAST ONE SILICON CONTAINING MOIETY OF GIVEN FORMULA; USE AS UV-B FILTERS IN LIGHT SCREENING COMPOSITIONS | ROCHE VITAMINS INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0933376-A2 | Silanyl-triazines as light screening compositions | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-04 | — | — | EP | disclosed |