Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7209949 | 0.88 | MMP13 (0.42) | MMP13MMP1CHRM1CHRM3RORC | |
| SCHEMBL7290264 | 0.85 | MMP13 (0.55) | MMP13MMP1CHRM1CHRM3RORC | |
| SCHEMBL7209955 | 0.82 | KAT6A (0.35) | MMP13MMP1CHRM1CHRM3RORC | |
| SCHEMBL7204063 | 0.73 | MMP13 (0.53) | MMP13MMP1MMP2MMP9 | |
| SCHEMBL7202562 | 0.73 | MMP13 (0.55) | MMP13MMP1CA1CA2MMP2 | |
| SCHEMBL7205953 | 0.73 | MMP13 (0.71) | MMP13MMP1MMP2MMP9MMP8 | |
| SCHEMBL7199642 | 0.73 | MMP13 (0.57) | MMP13MMP1MMP2MMP9MMP8 | |
| SCHEMBL7201763 | 0.73 | MMP13 (0.55) | MMP13MMP1MMP2MMP9 | |
| SCHEMBL7201008 | 0.72 | MMP13 (0.54) | MMP13MMP1MMP2MMP9MMP8 | |
| SCHEMBL7290273 | 0.71 | MGLL (0.41) | MMP13MMP1RORCCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608104-B2 | Antiarthritic agents; anticancer agents | PFIZER INC | 2003-08-19 | — | — | US | disclosed |