Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204066 | 0.90 | ALDH1A1 (0.38) | MGLLMMP13CA12CA1CA2 | |
| SCHEMBL7201014 | 0.90 | SMN1; SMN2 (0.41) | MMP13CA12CA1CA2CA7 | |
| SCHEMBL7202567 | 0.88 | MMP13 (0.40) | MMP13CA12CA1CA2CA7 | |
| SCHEMBL7205956 | 0.88 | MMP13 (0.53) | MMP13MMP1F10KDM2BMEN1 | |
| SCHEMBL7201767 | 0.86 | NAAA (0.44) | MMP13CA12CA1CA2CA7 | |
| SCHEMBL7199646 | 0.86 | MMP1 (0.43) | MGLLMMP13MMP1 | |
| SCHEMBL7300738 | 0.83 | MMP13 (0.48) | MMP13MMP1MEN1KMT2A | |
| SCHEMBL7201540 | 0.83 | ADAMTS4 (0.39) | MMP13CA12CA1CA2CA7 | |
| SCHEMBL7292292 | 0.83 | AKR1C3 (0.45) | MMP13MMP1F2F10PLG | |
| SCHEMBL7200563 | 0.83 | MMP1 (0.57) | MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138680-A1 | Gem substituted sulfonyl hydroxamic acids as MMP inhibitors | Pfizer Products Inc. (US) | 2001-10-04 | — | — | EP | disclosed |