Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215312 | 0.76 | ADRA2B (0.47) | MAPT | |
| SCHEMBL23981547 | 0.74 | MAPK1 (0.49) | KMT2AALDH1A1CYP1A2MEN1RXFP1 | |
| SCHEMBL29263634 | 0.72 | GLS (0.36) | KMT2AALDH1A1MEN1RXFP1MAPT | |
| SCHEMBL31035986 | 0.72 | GLS (0.36) | KMT2AALDH1A1MEN1RXFP1MAPT | |
| SCHEMBL6218882 | 0.71 | ALDH1A1 (0.47) | KMT2AALDH1A1HIF1AMEN1RXFP1 | |
| SCHEMBL16207595 | 0.71 | ALDH1A1 (0.53) | KMT2AALDH1A1HIF1ACYP1A2MEN1 | |
| SCHEMBL17083672 | 0.71 | ALDH1A1 (0.53) | KMT2AALDH1A1HIF1ACYP1A2MEN1 | |
| SCHEMBL9994102 | 0.71 | CYP19A1 (0.51) | KMT2AALDH1A1HIF1ACYP19A1CYP11B1 | |
| SCHEMBL19332416 | 0.70 | MAPT (0.50) | KMT2AALDH1A1MEN1RXFP1MAPT | |
| SCHEMBL30963305 | 0.70 | ALDH1A1 (0.44) | KMT2AALDH1A1CYP1A2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617339-B1 | 5-Isoxazolyloxymethyl-3-((dihydroxypropanoyl)-4-tetrahydropyri dyl-3,5- difluorophenyl)oxazolidinone, or the phosphated derivative or its disodium salt; antibiotic with useful activity against Grampositive pathogens | SYNGENTA LIMITED (GB) | 2003-09-09 | — | — | US | disclosed |