Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201527 | 0.82 | P2RX7 (0.41) | MAPTGAAXBP1KDM4EL3MBTL1 | |
| SCHEMBL4105640 | 0.79 | CYP2D6 (0.37) | MAPTGAAXBP1KDM4EL3MBTL1 | |
| SCHEMBL4103952 | 0.75 | KMT2A (0.43) | MAPTGAAXBP1KDM4EALDH1A1 | |
| SCHEMBL7211598 | 0.74 | CYP2D6 (0.37) | MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL15612078 | 0.73 | KMT2A (0.37) | GAAKDM4EALDH1A1RAB9ANFKB1 | |
| SCHEMBL9079943 | 0.73 | CYP2D6 (0.37) | — | |
| SCHEMBL11070416 | 0.71 | GAA (0.34) | MAPTGAAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL1634162 | 0.70 | GAA (0.72) | MAPTGAAXBP1KDM4EPOLB | |
| SCHEMBL7703026 | 0.70 | MAPT (0.37) | MAPT | |
| SCHEMBL7211051 | 0.70 | CYP2C19 (0.41) | KDM4EPOLBNFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307493-A2 | POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME | Goodrich Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010231-A2 | POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME | GOODRICH CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |