Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | GUSB | P08236 | 10/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 2/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034149 | 0.85 | NR4A2 (0.70) | NR4A2GUSBRAB9AMPOPCSK9 | |
| SCHEMBL989756 | 0.84 | NR4A2 (0.73) | NR4A2RAB9ABRPF1 | |
| SCHEMBL6029339 | 0.82 | ALDH1A1 (0.62) | NR4A2RAB9ABRPF1 | |
| SCHEMBL14486971 | 0.82 | NR4A2 (0.62) | NR4A2RAB9ABRPF1 | |
| SCHEMBL6029970 | 0.82 | NR4A2 (0.51) | NR4A2BRPF1 | |
| SCHEMBL1559436 | 0.81 | RAB9A (0.49) | GUSBRAB9AMPOPCSK9BRPF1 | |
| SCHEMBL14555755 | 0.79 | ALDH1A1 (0.49) | NR4A2GUSBPCSK9GPR84 | |
| SCHEMBL2035484 | 0.79 | GPR84 (0.53) | GUSBRAB9AMPOPCSK9BRPF1 | |
| SCHEMBL6329279 | 0.79 | NR4A2 (0.48) | NR4A2BRPF1 | |
| Hydrochloric Acid SCHEMBL14487429 | 0.78 | ALDH1A1 (0.48) | NR4A2GUSBPCSK9GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337527-A1 | INDOLYLMALEIMIDE DERIVATIVES AS PROTEIN KINASE C INHIBITORS | Novartis AG (CH) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002038561-A1 | INDOLYLMALEIMIDE DERIVATIVES AS PROTEIN KINASE C INHIBITORS | NOVARTIS AG (CH) | 2002-05-16 | — | — | WO | disclosed |