Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.71 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.71 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.65 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.65 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.65 |
| ▸ | CES2 | O00748 | 1/20 | 0.65 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.63 |
| ▸ | PRKCA | P17252 | 1/20 | 0.63 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.61 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.61 |
| ▸ | SELP | P16109 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715504 | 1.00 | LPAR1 (0.71) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL7153767 | 0.97 | S1PR1 (0.69) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL2328212 | 0.93 | ENPP2 (0.81) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL15328013 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL173282 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL200646 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL7698286 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL3817083 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL235478 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 | |
| SCHEMBL15328011 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3ENPP2SMN1; SMN2LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733645-B1 | NOVEL SYNTHETIC PEPTIDE, LUNG SURFACTANT CONTAINING THE SAME, AND REMEDY FOR RESPIRATORY DISTRESS SYNDROME | MITSUBISHI PHARMA CORP (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-5827825-A | POLYPEPTIDE FROM THE CONDENSATION OF VARIABLE HEXA- OR HEPTAPEPTIDES WITH PEPTIDES CONTAINING TWELVE TO TWENTY UNITS OF LEUCINE AND/OR NORLEUCINE, FOR TREATMENT OF RESPIRATORY DISORDERS | TOKYO TANABE COMPANY LTD. (JP) | 1998-10-27 | — | — | US | disclosed |
| EP-0733645-A1 | NOVEL SYNTHETIC PEPTIDE, LUNG SURFACTANT CONTAINING THE SAME, AND REMEDY FOR RESPIRATORY DISTRESS SYNDROME | TOKYO TANABE COMPANY LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |