SCHEMBL9715504

SCHEMBL9715504

CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COC(=O)[C@@H](N)COP(=O)(O)O)OC(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 9/20 0.71
LPAR3 Q9UBY5 5/20 0.71
ENPP2 Q13822 4/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
LPAR4 Q99677 2/20 0.65
LPAR5 Q9H1C0 2/20 0.65
LPAR2 Q9HBW0 2/20 0.65
CES2 O00748 1/20 0.65
LPAR6 P43657 1/20 0.65
TRPV1 Q8NER1 1/20 0.65
S1PR1 P21453 1/20 0.64
PRKCE Q02156 1/20 0.63
PRKCQ Q04759 1/20 0.63
PRKCD Q05655 1/20 0.63
PRKCA P17252 1/20 0.63
P2RY10 O00398 1/20 0.61
GPR174 Q9BXC1 1/20 0.61
SELP P16109 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7210663 1.00 LPAR1 (0.71) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL7153767 0.97 S1PR1 (0.69) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL2328212 0.93 ENPP2 (0.81) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL15328013 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL173282 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL200646 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL7698286 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL3817083 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL235478 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4
SCHEMBL15328011 0.91 LPAR1 (0.85) LPAR1LPAR3ENPP2SMN1; SMN2LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504328-B2 Method for preparing liposome comprising ultrasound reactive microbubble for drug delivery and liposome using same BIOINFRA LIFE SCIENCE INC. (KR) 2022-11-22 US claimed
CN-113873998-A Liposome formulations and methods of use and preparation thereof 糖胺公司 2021-12-31 CN claimed
WO-2019182353-A1 METHOD FOR PREPARING LIPOSOME COMPRISING ULTRASOUND REACTIVE MICROBUBBLE FOR DRUG DELIVERY AND LIPOSOME USING SAME (주) 바이오인프라생명과학 2019-09-26 WO claimed
EP-0358640-B1 DEHYDRATING VESICULE PREPARATIONS FOR LONG-TERM STORAGE VESTAR, INC. (US) 1992-09-16 EP claimed
CN-115315252-A Antiviral composition for preventing or treating infection or respiratory disease after exposure 盈擘医药股份有限公司 2022-11-08 CN disclosed
CN-115003337-A Biocompatible oily ferrofluid and preparation method thereof 波尔多大学 2022-09-02 CN disclosed
CN-113116825-A Lipid cake for preparing anesthetic composition and preparation method thereof 美商TLC生物医药公司 2021-07-16 CN disclosed
CN-110974954-B Lipid nanoparticle for enhancing immune effect of nucleic acid vaccine and preparation method thereof 珠海丽凡达生物技术有限公司 2021-03-16 CN disclosed
CN-112384204-A Tolerogenic liposomes and methods of use thereof 安托瑞斯公司 2021-02-19 CN disclosed
CN-111867564-A Slow-release anesthetic composition and preparation method thereof 美商TLC生物医药公司 2020-10-30 CN disclosed
CN-111164068-A Biodegradable compound, lipid particle, composition containing lipid particle, and kit 株式会社东芝 2020-05-15 CN disclosed
CN-110974954-A Lipid nanoparticle for enhancing immune effect of nucleic acid vaccine and preparation method thereof 珠海丽凡达生物技术有限公司 2020-04-10 CN disclosed
WO-2019182353-A1 METHOD FOR PREPARING LIPOSOME COMPRISING ULTRASOUND REACTIVE MICROBUBBLE FOR DRUG DELIVERY AND LIPOSOME USING SAME (주) 바이오인프라생명과학 2019-09-26 WO disclosed
EP-0282564-A4 INHIBITION OF PROTEIN KINASE C BY LONG-CHAIN BASES 1991-09-11 EP disclosed
US-4937232-A Inhibition of protein kinase C by long-chain bases DUKE UNIVERSITY (US) 1990-06-26 US disclosed
US-4816450-A ANTIINFLAMMATORY AGENTS, AMINE COMPOUNDS DUKE UNIVERSITY (US) 1989-03-28 US disclosed
EP-0282564-A1 INHIBITION OF PROTEIN KINASE C BY LONG-CHAIN BASES DUKE UNIVERSITY (US) 1988-09-21 EP disclosed
WO-1988001869-A1 INHIBITION OF PROTEIN KINASE C BY LONG-CHAIN BASES DUKE UNIVERSITY (US) 1988-03-24 WO disclosed