Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | DDX3X | O00571 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336123 | 0.86 | CPN1 (0.43) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL27493979 | 0.85 | ADRB1 (0.40) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL5796124 | 0.84 | APP (0.47) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL8909021 | 0.84 | ADRB1 (0.46) | ADRB2ADRB1ADRB3SLC7A5LMNA | |
| SCHEMBL27494783 | 0.84 | ADRB2 (0.40) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL27533952 | 0.83 | SLC7A5 (0.37) | SLC7A5ALDH1A1LMNAKMT2AATM | |
| SCHEMBL7347467 | 0.82 | CPN1 (0.47) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL7461910 | 0.82 | CPN1 (0.47) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL7461918 | 0.82 | CPN1 (0.40) | CPN1CPB2ADRB2ADRB1ADRB3 | |
| SCHEMBL28741995 | 0.82 | CPN1 (0.40) | CPN1CPB2ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |