SCHEMBL28741995

SCHEMBL28741995

CC(C)(C)OC(=O)C(c1cccc(N)c1)C(C)(C)N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.40
CPB2 Q96IY4 1/20 0.40
ADRB2 P07550 2/20 0.40
ADRB1 P08588 2/20 0.40
ADRB3 P13945 2/20 0.40
HPGDS O60760 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
NR1H2 P55055 1/20 0.34
SLC7A5 Q01650 1/20 0.34
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
PBRM1 Q86U86 1/20 0.33
DDX3X O00571 1/20 0.33
APP P05067 1/20 0.32
MAPKAPK2 P49137 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7336123 0.83 CPN1 (0.43) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL7210714 0.82 CPN1 (0.42) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL5796124 0.82 APP (0.47) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL27493979 0.79 ADRB1 (0.40) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL7461910 0.79 CPN1 (0.47) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL7461918 0.79 CPN1 (0.40) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL7347467 0.79 CPN1 (0.47) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL27494783 0.78 ADRB2 (0.40) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL28006901 0.77 CPN1 (0.48) CPN1CPB2ADRB2ADRB1ADRB3
SCHEMBL6546992 0.76 CTSK (0.47) CPN1CPB2ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1217936-C Heterocyclic compounds having sulfonic acid EISAI CO LTD (JP) 2005-09-07 CN disclosed
CN-1414952-A Heterocyclic compounds having sulfonic acid EISAI CO LTD (JP) 2003-04-30 CN disclosed