SCHEMBL7211632

SCHEMBL7211632

O=S(=O)(c1ccc(S)c(S)c1)N1CCOCC1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.62
TSHR P16473 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
LMNA P02545 2/20 0.57
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
GAA P10253 2/20 0.55
KDM4E B2RXH2 3/20 0.55
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 2/20 0.55
PKM P14618 1/20 0.55
CASP1 P29466 1/20 0.55
HPGD P15428 1/20 0.55
HTR2C P28335 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666586 0.98 POLB (0.60) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL7212968 0.83 USP2 (0.66) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL16312927 0.82 TSHR (0.53) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL20380049 0.82 ALDH1A1 (0.63) POLBSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL12793245 0.82 POLB (0.88) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL7212954 0.81 USP2 (0.63) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL7207141 0.81 USP2 (0.63) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL1269596 0.81 POLB (0.73) POLBTSHRSMN1; SMN2LMNAMEN1
SCHEMBL8046782 0.79 L3MBTL1 (0.53) POLBSMN1; SMN2LMNAKDM4EALDH1A1
SCHEMBL16735251 0.78 LMNA (0.62) POLBTSHRSMN1; SMN2LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841340-B1 SUBSTITUTED BENZENEDITHIOL-METAL COMPLEXES SUMITOMO SEIKA CHEMICALS (JP) 2002-06-19 EP claimed
US-5856520-A OPTICAL RECORDING MEDIA SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-01-05 US claimed
EP-0841340-A1 SUBSTITUTED BENZENEDITHIOL-METAL COMPLEXES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-05-13 EP claimed
EP-0905202-B1 PHOTOSTABILIZED CYANINE DYES AND OPTICAL RECORDING MEDIUM TDK CORP (JP) 2003-03-19 EP disclosed
EP-0841340-B1 SUBSTITUTED BENZENEDITHIOL-METAL COMPLEXES SUMITOMO SEIKA CHEMICALS (JP) 2002-06-19 EP disclosed
US-6071672-A QUATERNARY CYANINE DYE SALT WITH SUBSTITUTED BENZENEDITHIOL METAL COMPLEX ANION; COMPACT DISKS TDK CORPORATION (JP) 2000-06-06 US disclosed
US-5959152-A REACTING 3,4-DIBROMOBEZENESULFONYL CHLORIDE WITH AN AMINE OR AN AROMATIC HYDROCARBON TO FORM A SULFONE OR SULFONAMIDE; REACTING PRODUCT WITH SODIUM HYDROSULFIDE TO FORM DIMERCAPTAN SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-09-28 US disclosed
EP-0905202-A1 PHOTOSTABILIZED CYANINE DYES AND OPTICAL RECORDING MEDIUM TDK Corporation (JP) 1999-03-31 EP disclosed
US-5856520-A OPTICAL RECORDING MEDIA SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-01-05 US disclosed
EP-0841340-A1 SUBSTITUTED BENZENEDITHIOL-METAL COMPLEXES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-05-13 EP disclosed