Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | GGH | Q92820 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185212 | 0.81 | LMNA (0.41) | FOLH1CPA3ALDH1A1LMNATDP1 | |
| SCHEMBL6065012 | 0.81 | LMNA (0.41) | FOLH1CPA3ALDH1A1LMNATDP1 | |
| SCHEMBL28286136 | 0.80 | NR4A2 (0.41) | FOLH1CPA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL28287517 | 0.80 | LMNA (0.40) | FOLH1CPA3ALDH1A1LMNATDP1 | |
| SCHEMBL28286182 | 0.80 | LMNA (0.40) | FOLH1CPA3ALDH1A1LMNATDP1 | |
| SCHEMBL31266570 | 0.76 | CPA3 (0.42) | FOLH1CPA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL28797503 | 0.76 | CPA3 (0.42) | FOLH1CPA3ALDH1A1LMNAMAPK1 | |
| SCHEMBL8668465 | 0.75 | EGFR (0.37) | FOLH1CPA3ALDH1A1LMNATRPA1 | |
| SCHEMBL7511627 | 0.75 | EGFR (0.37) | FOLH1CPA3ALDH1A1LMNATRPA1 | |
| SCHEMBL4775104 | 0.73 | CPA3 (0.42) | FOLH1CPA3ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613563-B1 | Comprising antibody that binds an adenoviral capsid protein, ligand that binds the preselected receptor and adenovirus containing a nucleic acid molecule that encodes a gene product under the control of a promoter; use in gene therapy | SELECTIVE GENTICS, INC. | 2003-09-02 | — | — | US | disclosed |