Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511627 | 1.00 | EGFR (0.37) | EGFRERBB2POLBCPA3HSD17B10 | |
| SCHEMBL9210808 | 0.83 | ALDH1A1 (0.42) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL28797503 | 0.77 | CPA3 (0.42) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL31266570 | 0.77 | CPA3 (0.42) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL7211709 | 0.75 | FOLH1 (0.37) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL1083608 | 0.74 | CPA3 (0.42) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL4775104 | 0.74 | CPA3 (0.42) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL28129661 | 0.74 | FOLH1 (0.47) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL28129663 | 0.74 | FOLH1 (0.47) | POLBCPA3HSD17B10LMNATDP1 | |
| SCHEMBL1083606 | 0.74 | CPA3 (0.42) | POLBCPA3HSD17B10LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807688-A | ANTIBODY DIRECTED ANZYME PRODRUG THERAPY | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |