Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211940 | 0.92 | PTGS2 (0.73) | PTGS2PTGS1CA1CA2SOS1 | |
| SCHEMBL7210664 | 0.88 | PTGS2 (0.68) | PTGS2PTGS1CA2SOS1CHRNA7 | |
| SCHEMBL5314644 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL7216255 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL5309174 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL2463751 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL7211992 | 0.83 | PTGS2 (0.68) | PTGS2PTGS1CA2SOS1 | |
| SCHEMBL7215325 | 0.82 | PTGS2 (0.63) | PTGS2PTGS1CA1CA2 | |
| SCHEMBL5311727 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1CA1CA2CHRNA7 | |
| SCHEMBL7216189 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1CA1CA2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |