Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034573 | 0.82 | SIGMAR1 (0.56) | KMT2AALDH1A1LMNAMEN1HTT | |
| Hydrochloric Acid SCHEMBL7218696 | 0.81 | SIGMAR1 (0.55) | KMT2AALDH1A1LMNAMEN1HTT | |
| SCHEMBL9455598 | 0.80 | EBP (0.60) | KMT2AALDH1A1LMNAMEN1HTT | |
| SCHEMBL9036801 | 0.80 | MAPK1 (0.54) | KMT2AALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL7212383 | 0.79 | SETD7 (0.56) | KMT2AALDH1A1LMNAMEN1HTT | |
| Hydrochloric Acid SCHEMBL7217927 | 0.79 | EBP (0.58) | KMT2AALDH1A1LMNAMEN1HTT | |
| Hydrochloric Acid SCHEMBL7212374 | 0.78 | SETD7 (0.55) | KMT2AALDH1A1LMNAMEN1HTT | |
| Hydrochloric Acid SCHEMBL7217686 | 0.78 | SETD7 (0.58) | KMT2AALDH1A1LMNAMEN1HTT | |
| SCHEMBL2862536 | 0.76 | FAAH (0.54) | KMT2AALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL9035896 | 0.76 | SIGMAR1 (0.54) | KMT2AALDH1A1LMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38257-E1 | Piperdine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 2003-09-23 | — | — | US | disclosed |
| US-5393890-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1995-02-28 | — | — | US | disclosed |