Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7212711 | 0.99 | SIGMAR1 (0.53) | SIGMAR1SETD7HTR1ACTNNB1WNT3A | |
| SCHEMBL7299683 | 0.94 | SETD7 (0.53) | SIGMAR1SETD7HTR1ACTNNB1WNT3A | |
| SCHEMBL9034437 | 0.93 | SETD7 (0.54) | SIGMAR1SETD7HTR1ACTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL9034533 | 0.93 | SETD7 (0.52) | SIGMAR1SETD7HTR1ACTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL7212361 | 0.92 | SETD7 (0.53) | SIGMAR1SETD7HTR1ACTNNB1WNT3A | |
| SCHEMBL7299134 | 0.90 | SETD7 (0.51) | SIGMAR1SETD7HTR1AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7212583 | 0.89 | ALDH1A1 (0.50) | SIGMAR1SETD7HTR1AALDH1A1HTT | |
| SCHEMBL9591385 | 0.86 | SETD7 (0.44) | SIGMAR1SETD7HTR1ACTNNB1WNT3A | |
| SCHEMBL7212545 | 0.84 | SETD7 (0.46) | SIGMAR1SETD7HTR1AALDH1A1HTT | |
| SCHEMBL7212442 | 0.84 | SETD7 (0.53) | SETD7HTR1AALDH1A1HTTABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |