Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217691 | 0.89 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4EGAACYP2C19 | |
| SCHEMBL7299134 | 0.84 | SETD7 (0.51) | MAPK1ALDH1A1SMN1; SMN2KDM4ECYP2C19 | |
| Hydrochloric Acid SCHEMBL7212583 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KDM4ECYP2C19MAPT | |
| SCHEMBL9035896 | 0.82 | SIGMAR1 (0.54) | MAPK1ALDH1A1KDM4ECYP2C19MAPT | |
| SCHEMBL7213758 | 0.81 | TSHR (0.54) | ALDH1A1GAACYP2C19MAPTPOLB | |
| Hydrochloric Acid SCHEMBL7212711 | 0.81 | SIGMAR1 (0.53) | MAPK1ALDH1A1KDM4ECYP2C19MAPT | |
| SCHEMBL7299683 | 0.80 | SETD7 (0.53) | ALDH1A1CYP2C19MAPTPOLBLMNA | |
| SCHEMBL7212409 | 0.80 | KMT2A (0.50) | ALDH1A1SMN1; SMN2GAACYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL9034533 | 0.79 | SETD7 (0.52) | ALDH1A1CYP2C19MAPTPOLBLMNA | |
| SCHEMBL9034437 | 0.79 | SETD7 (0.54) | ALDH1A1KDM4ECYP2C19POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |