Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299683 | 0.90 | SETD7 (0.53) | SETD7ALDH1A1HTTDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9034533 | 0.89 | SETD7 (0.52) | SETD7ALDH1A1HTTDRD2HTR2A | |
| SCHEMBL9034437 | 0.87 | SETD7 (0.54) | SETD7ALDH1A1HTTDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7212361 | 0.87 | SETD7 (0.53) | SETD7ALDH1A1HTTDRD2HTR2A | |
| SCHEMBL7212540 | 0.85 | SETD7 (0.52) | SETD7ALDH1A1HTTDRD2HTR2A | |
| SCHEMBL9034771 | 0.85 | HTR1A (0.61) | SETD7ALDH1A1HTTDRD2HTR2A | |
| SCHEMBL9035896 | 0.84 | SIGMAR1 (0.54) | SETD7ALDH1A1HTTDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7212711 | 0.83 | SIGMAR1 (0.53) | SETD7ALDH1A1HTTTAAR1DRD2 | |
| SCHEMBL7218874 | 0.83 | SETD7 (0.58) | SETD7ALDH1A1HTTDRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9034034 | 0.82 | SETD7 (0.59) | SETD7ALDH1A1HTTDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| US-RE38257-E1 | Piperdine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 2003-09-23 | — | — | US | disclosed |