Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9034533 | 0.99 | SETD7 (0.52) | SETD7SIGMAR1DRD2DRD4ALDH1A1 | |
| SCHEMBL9034437 | 0.97 | SETD7 (0.54) | SETD7SIGMAR1DRD2DRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7212361 | 0.96 | SETD7 (0.53) | SETD7SIGMAR1DRD2DRD4ALDH1A1 | |
| SCHEMBL9035896 | 0.94 | SIGMAR1 (0.54) | SETD7SIGMAR1DRD2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7212711 | 0.93 | SIGMAR1 (0.53) | SETD7SIGMAR1DRD2ALDH1A1HTR1A | |
| SCHEMBL9591385 | 0.91 | SETD7 (0.44) | SETD7SIGMAR1DRD2DRD4ALDH1A1 | |
| SCHEMBL7212442 | 0.90 | SETD7 (0.53) | SETD7DRD2DRD4ALDH1A1POLB | |
| SCHEMBL9036537 | 0.89 | DRD2 (0.51) | SETD7SIGMAR1DRD2DRD4ALDH1A1 | |
| SCHEMBL7299134 | 0.88 | SETD7 (0.51) | SETD7SIGMAR1DRD2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL7213794 | 0.88 | SETD7 (0.53) | SETD7DRD2DRD4ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |