Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216196 | 0.93 | NPSR1 (0.44) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL7217207 | 0.85 | KCNN4 (0.46) | SMN1; SMN2KMT2AKCNN4KIF11ALDH1A1 | |
| SCHEMBL7217326 | 0.77 | KCNN4 (0.48) | SMN1; SMN2KMT2AKCNN4KIF11ALDH1A1 | |
| SCHEMBL4590400 | 0.75 | MAPT (0.50) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL5012067 | 0.74 | TSHR (0.52) | NPSR1CYP1A2LMNAMAPTKMT2A | |
| Hydroxyphenamate SCHEMBL546919 | 0.71 | KMT2A (0.42) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| Hydroxyphenamate SCHEMBL5704281 | 0.71 | KMT2A (0.42) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL6497924 | 0.69 | MAPT (0.42) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL13275212 | 0.69 | LMNA (0.42) | SMN1; SMN2LMNAMAPK1HIF1AHTT | |
| Urethane SCHEMBL3680047 | 0.68 | ALOX15 (0.56) | NPSR1CYP1A2CYP2D6PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156798-B1 | FELBAMATE DERIVED COMPOUNDS | UNIV VIRGINIA (US) | 2003-07-09 | — | — | EP | claimed |