Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974675 | 0.87 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBGLO1HSD17B10 | |
| SCHEMBL9701061 | 0.86 | THRB (0.62) | ALDH1A1TSHRTHRBGLO1HSD17B10 | |
| SCHEMBL3768916 | 0.84 | THRB (0.60) | ALDH1A1TSHRTHRBGLO1HSD17B10 | |
| SCHEMBL15302627 | 0.84 | THRB (0.60) | ALDH1A1TSHRTHRBGLO1HSD17B10 | |
| SCHEMBL3691310 | 0.82 | THRB (0.58) | ALDH1A1TSHRTHRBGLO1HSD17B10 | |
| SCHEMBL1039741 | 0.82 | MEN1 (0.42) | ALDH1A1TSHRTHRBHSD17B10TP53 | |
| SCHEMBL1035521 | 0.82 | MEN1 (0.42) | ALDH1A1TSHRTHRBHSD17B10TP53 | |
| SCHEMBL1034843 | 0.82 | MEN1 (0.42) | ALDH1A1TSHRTHRBHSD17B10TP53 | |
| SCHEMBL52704 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBGLO1HSD17B10 | |
| SCHEMBL10589400 | 0.81 | THRB (0.56) | ALDH1A1TSHRTHRBGLO1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177227-B1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORP (US) | 2003-10-01 | — | — | EP | claimed |
| US-20020128417-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-09-12 | — | — | US | claimed |
| EP-1177227-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2002-02-06 | — | — | EP | claimed |
| US-20020007032-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-01-17 | — | — | US | claimed |
| US-20010056165-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2001-12-27 | — | — | US | claimed |
| US-6281319-B1 | HYDRATABLE POLYMER | SURGIDEV CORPORATION | 2001-08-28 | — | — | US | claimed |
| WO-2000061646-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2000-10-19 | — | — | WO | claimed |