Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677565 | 0.79 | GAA (0.39) | SMN1; SMN2MEN1KMT2ATTRCYP3A4 | |
| SCHEMBL10061749 | 0.79 | RIPK1 (0.44) | SMN1; SMN2CYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL28114102 | 0.76 | MEN1 (0.44) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11861084 | 0.73 | AR (0.38) | SMN1; SMN2CYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL2019079 | 0.70 | MEN1 (0.40) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8730306 | 0.70 | MAPT (0.45) | SMN1; SMN2CYP3A4ALDH1A1CYP2D6KDM4E | |
| SCHEMBL1674630 | 0.70 | GAA (0.45) | SMN1; SMN2CYP2C19CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL29408555 | 0.69 | AR (0.50) | SMN1; SMN2CYP2C19CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL3871304 | 0.69 | AR (0.50) | SMN1; SMN2CYP2C19CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL2558366 | 0.68 | AKR1B1 (0.55) | SMN1; SMN2TTRCYP1A2ADRA1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101874033-B | The manufacture method of organic alkali metal compound and organo-transition metal compound | MITSUI CHEMICALS, INC. (JP) | 2016-05-11 | — | — | CN | disclosed |
| EP-2226326-B1 | METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND | MITSUI CHEMICALS INC (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-8409480-B2 | Process for preparing organic alkali metal compound and organic transition metal compound | MITSUI CHEMICALS, INC. (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20120049391-A1 | PROCESS FOR PREPARING ORGANIC ALKALI METAL COMPOUND AND ORGANIC TRANSITION METAL COMPOUND | MITSUI CHEMICALS, INC. | 2012-03-01 | — | — | US | disclosed |
| EP-2226326-A1 | METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND | Mitsui Chemicals, Inc. (JP) | 2010-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049391-A1 | PROCESS FOR PREPARING ORGANIC ALKALI METAL COMPOUND AND ORGANIC TRANSITION METAL COMPOUND | NHP2, SSRP1, RER1 | SMN1; SMN2 1788/4885CHRM2 2566/4885CHRM4 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.