Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517092 | 0.78 | HPGD (0.62) | HPGDCYP1A2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL2576585 | 0.74 | RAB9A (0.45) | HPGDMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL29938206 | 0.74 | RAB9A (0.45) | HPGDMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8523177 | 0.73 | BCAT2 (0.53) | HPGDCYP1A2MAPTALDH1A1CYP3A4 | |
| SCHEMBL1719706 | 0.71 | AKR1C3 (0.44) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL3459359 | 0.70 | CA1 (0.70) | HPGDCYP1A2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5885064 | 0.70 | HPGD (0.68) | HPGDCYP1A2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7978017 | 0.70 | HPGD (0.68) | HPGDCYP1A2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL18586564 | 0.69 | HPGD (0.62) | HPGDCYP1A2MAPTALDH1A1L3MBTL1 | |
| Acrylic Acid SCHEMBL8518733 | 0.69 | GSTO1 (0.42) | HPGDCYP1A2MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003183263-A | N-ALKYL-ADAMANTYLTRIAZINYLBENZAMIDE DERIVATIVE | PFIZER PROD INC | 2003-07-03 | — | — | JP | disclosed |