Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.45 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19054962 | 0.86 | BRPF1 (0.53) | PGRCREBBPBRPF1IDO1PARP1 | |
| SCHEMBL260994 | 0.86 | BRPF1 (0.53) | PGRCREBBPBRPF1IDO1PARP1 | |
| SCHEMBL30088920 | 0.86 | BRPF1 (0.53) | PGRCREBBPBRPF1IDO1PARP1 | |
| SCHEMBL875747 | 0.73 | BRPF1 (0.47) | PGRACVR1CREBBPBRPF1IDO1 | |
| SCHEMBL8294613 | 0.73 | BRPF1 (0.47) | PGRACVR1CREBBPBRPF1IDO1 | |
| SCHEMBL14169780 | 0.72 | CREBBP (0.65) | PGRACVR1CREBBPBRPF1IDO1 | |
| SCHEMBL24112743 | 0.70 | PGR (0.46) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13091038 | 0.70 | PGR (0.46) | PGRBMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL13366003 | 0.70 | HTR5A (0.48) | CREBBPBRPF1MAPTGAA | |
| SCHEMBL31474673 | 0.70 | HTR5A (0.48) | CREBBPBRPF1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990637-A4 | PROCESS FOR PRODUCING KETOPROFEN AND 5-BENZOYL-3-METHYL-2-INDOLINONE | MEDICAL INFORMATION SERVICES I (JP) | 2003-01-02 | — | — | EP | disclosed |
| WO-1998049127-A1 | PROCESS FOR PRODUCING KETOPROFEN AND 5-BENZOYL-3-METHYL-2-INDOLINONE | MEDICAL INFORMATION SERVICES, INC. (JP) | 1998-11-05 | — | — | WO | disclosed |