SCHEMBL260994

SCHEMBL260994

CC1C(=O)Nc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 1/20 0.53
CREBBP Q92793 1/20 0.53
IDO1 P14902 4/20 0.50
PGR P06401 2/20 0.50
PARP1 P09874 1/20 0.48
MAPT P10636 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 2/20 0.45
GAA P10253 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GSK3B P49841 2/20 0.45
HTR5A P47898 2/20 0.43
TDO2 P48775 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30088920 1.00 BRPF1 (0.53) BRPF1CREBBPIDO1PGRPARP1
SCHEMBL19054962 1.00 BRPF1 (0.53) BRPF1CREBBPIDO1PGRPARP1
SCHEMBL7213330 0.86 PGR (0.55) BRPF1CREBBPIDO1PGRPARP1
SCHEMBL8294613 0.84 BRPF1 (0.47) BRPF1CREBBPIDO1PGRPARP1
SCHEMBL875747 0.84 BRPF1 (0.47) BRPF1CREBBPIDO1PGRPARP1
SCHEMBL14169780 0.84 CREBBP (0.65) BRPF1CREBBPIDO1PGRPARP1
SCHEMBL13366003 0.81 HTR5A (0.48) BRPF1CREBBPMAPTGAAHTR5A
SCHEMBL31474673 0.81 HTR5A (0.48) BRPF1CREBBPMAPTGAAHTR5A
SCHEMBL6220534 0.81 BRPF1 (0.52) BRPF1CREBBPIDO1PARP1MAPT
SCHEMBL5496567 0.79 PDK2 (0.44) BRPF1CREBBPIDO1PGRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
WO-2025019764-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS MATTERWORKS INC (US) 2025-01-23 WO claimed
CN-118668266-A Cyanide-free electroless gold plating solution applied to wafer 深圳市溢诚电子科技有限公司 2024-09-20 CN claimed
CN-115701440-B Polyimide composite film, preparation method thereof and electronic equipment 华为技术有限公司 2024-07-30 CN claimed
CN-116656352-B Eutectic solvent and preparation method and application thereof 河北科技大学 2024-05-10 CN claimed
CN-116656352-A Eutectic solvent and preparation method and application thereof 河北科技大学 2023-08-29 CN claimed
US-20230137741-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2023-05-04 US claimed
WO-2023077166-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC (US) 2023-05-04 WO claimed
US-20160331725-A1 USE OF COMPOUNDS THAT ARE ABLE TO INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASE STATES ASSOCIATED WITH A REDUCED IGF-1 SERUM LEVEL IN HUMANS AND ANIMALS VEIJLEN N.V. 2016-11-17 US claimed
US-20150374662-A1 INHIBITORS OF BETA-CATENIN IN TREATMENT OF COLORECTAL CANCER REGENTS OF THE UNIVERSITY OF MINNESOTA 2015-12-31 US claimed
CN-1253543-A Process for producing ketoprofen and 5-benzoyl-3-methyl-2-indolinone MEDICAL INFORMATION SERVICES I (JP) 2000-05-17 CN claimed
EP-0990637-A1 PROCESS FOR PRODUCING KETOPROFEN AND 5-BENZOYL-3-METHYL-2-INDOLINONE Medical Information Services, Inc. (JP) 2000-04-05 EP claimed
EP-0460679-B1 Endothelin antagonistic peptide derivatives BANYU PHARMA CO LTD (JP) 1998-10-28 EP claimed
US-5691315-A CARDIOVASCULAR DISORDERS; VASODILATOR; BRONCHODILATOR BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-11-25 US claimed
US-5470833-A Vasodilators, bronchodilators BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-11-28 US claimed
US-5444152-A Vasolidator or bronchodilator BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-08-22 US claimed
EP-0626174-A2 Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-30 EP claimed
EP-0460679-A2 Endothelin antagonistic peptide derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1991-12-11 EP claimed
US-4845281-A Method of preparing ketoprofen BLASCHIM, S.P.A. (IT) 1989-07-04 US claimed
EP-0309009-A1 Process for preparing ketoprofen Nobel Chemicals AB (SE) 1989-03-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374662-A1 INHIBITORS OF BETA-CATENIN IN TREATMENT OF COLORECTAL CANCER CTNNB1, APC, CTNNBL1 BRPF1 2306/4885CREBBP 179/4885IDO1 3719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.