Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373935 | 0.91 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL7373273 | 0.84 | F2 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7219492 | 0.79 | F10 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7219528 | 0.75 | ITGB3 (0.83) | ITGB3ITGA2B | |
| SCHEMBL7219511 | 0.75 | ITGB3 (0.83) | ITGB3ITGA2B | |
| SCHEMBL7748060 | 0.75 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL9234147 | 0.71 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL7848502 | 0.71 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7847593 | 0.70 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL7090791 | 0.68 | ITGB3 (0.89) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | claimed |
| US-6623981-B2 | Detecting antibodies which bind integrin bound modulators; obtain sample, incubate with modulators and antibodies, form complexes, screen for bound complex | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-23 | — | — | US | disclosed |
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |