Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976930 | 0.74 | TGFBR1 (0.45) | TGFBR1MMP13 | |
| SCHEMBL7950060 | 0.72 | ITGB3 (0.51) | ITGB3ITGA2BTGFBR1MMP13YAP1 | |
| SCHEMBL7213411 | 0.71 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL7753284 | 0.70 | MMP13 (0.47) | TGFBR1MMP13 | |
| SCHEMBL7753620 | 0.69 | TGFBR1 (0.47) | ITGB3ITGA2BTGFBR1MMP13YAP1 | |
| SCHEMBL6969887 | 0.69 | TGFBR1 (0.49) | TGFBR1MMP13 | |
| SCHEMBL7503852 | 0.69 | ITGB3 (0.54) | ITGB3ITGA2BTGFBR1MMP13STS | |
| SCHEMBL7753201 | 0.69 | MMP13 (0.46) | ITGB3ITGA2BTGFBR1MMP13 | |
| SCHEMBL7752668 | 0.68 | KDM4E (0.51) | TGFBR1MMP13 | |
| SCHEMBL7349585 | 0.68 | ITGB3 (0.52) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |