Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220043 | 0.86 | CYP2E1 (0.37) | KMT2AMEN1KDM5AARPRKCQ | |
| SCHEMBL7215525 | 0.78 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL7215542 | 0.76 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL7219105 | 0.76 | CYP2E1 (0.49) | L3MBTL1ALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL7215529 | 0.74 | KDM5A (0.39) | L3MBTL1ALDH1A1HPGDMAPK1KDM4E | |
| SCHEMBL21736855 | 0.73 | KDM5A (0.39) | ALDH1A1MAPK1KDM4EHSD17B10KDM5A | |
| SCHEMBL29467123 | 0.71 | TYR (0.39) | L3MBTL1ALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL29739420 | 0.71 | ALDH1A1 (0.36) | L3MBTL1ALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL6472029 | 0.71 | CYP2E1 (0.48) | L3MBTL1ALDH1A1HPGDNPSR1RAB9A | |
| SCHEMBL21736854 | 0.71 | KDM5A (0.39) | L3MBTL1ALDH1A1HPGDMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |