Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013711 | 0.81 | ADRA1D (0.35) | ADRA1DADRA1AADRA1BPDE4AADORA2A | |
| SCHEMBL14639338 | 0.80 | ADORA2A (0.42) | ADRA1DADRA1AADRA1BPDE4AADORA2A | |
| SCHEMBL26948740 | 0.72 | ADORA2B (0.44) | PDE4AADORA2AADORA2BPDE4BPDE4C | |
| SCHEMBL11335748 | 0.72 | ADRA1D (0.31) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7833004 | 0.71 | ADRA1D (0.43) | ADRA1DADRA1AADRA1BPDE4AADORA2A | |
| SCHEMBL8477439 | 0.70 | NPC1 (0.43) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8952367 | 0.70 | ADRA1D (0.33) | ADRA1DADRA1AADRA1B | |
| SCHEMBL13469216 | 0.70 | ADORA2A (0.35) | ADRA1DADRA1AADRA1BPDE4AADORA2A | |
| SCHEMBL26776276 | 0.68 | GRIN2D (0.30) | — | |
| SCHEMBL7274821 | 0.67 | ADORA2A (0.43) | PDE4AADORA2AADORA2BPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37979-E1 | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | MITSUBISHI CHEMICAL CORPORATION | 2003-02-04 | — | — | US | disclosed |