Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.42 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213477 | 0.80 | ADRA1D (0.36) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26948740 | 0.80 | ADORA2B (0.44) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8876920 | 0.79 | SLC9A1 (0.53) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7833004 | 0.78 | ADRA1D (0.43) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12657637 | 0.78 | ADORA2A (0.41) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27989701 | 0.78 | CYP1A2 (0.51) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13469216 | 0.77 | ADORA2A (0.35) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11335748 | 0.75 | ADRA1D (0.31) | ADRA1DADRA1AADRA1B | |
| SCHEMBL26776276 | 0.75 | GRIN2D (0.30) | — | |
| SCHEMBL13384451 | 0.75 | ADORA2A (0.39) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013013013-A2 | COMPOSITIONS AND METHODS FOR PRODUCING MODIFIED GLYCOPROTEINS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-01-24 | — | — | WO | disclosed |