Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | STK3 | Q13188 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453209 | 0.86 | GSK3B (0.40) | SMN1; SMN2MEN1KMT2ARAB9AGSK3B | |
| SCHEMBL7683895 | 0.85 | MAPK1 (0.42) | PDGFRBCYP1A2PIM1ALDH1A1 | |
| SCHEMBL7064321 | 0.84 | IDH1 (0.39) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A | |
| SCHEMBL6390531 | 0.80 | IDO1 (0.47) | SMN1; SMN2MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL5500501 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A | |
| SCHEMBL14895111 | 0.78 | LOXL2 (0.47) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A | |
| SCHEMBL25610999 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A | |
| SCHEMBL12068347 | 0.78 | GSK3B (0.49) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A | |
| SCHEMBL1917870 | 0.78 | ADORA3 (0.50) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A | |
| SCHEMBL8723967 | 0.78 | NOTUM (0.39) | SMN1; SMN2PDGFRBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |