Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6099706 | 0.79 | LMNA (0.42) | ALDH1A1LMNATDP1TSHRSLC22A1 | |
| SCHEMBL6099711 | 0.79 | LMNA (0.42) | ALDH1A1LMNATDP1TSHRSLC22A1 | |
| SCHEMBL6100619 | 0.76 | LMNA (0.42) | ALDH1A1LMNAADRB2ADRB1ADRB3 | |
| SCHEMBL6100614 | 0.76 | LMNA (0.42) | ALDH1A1LMNAADRB2ADRB1ADRB3 | |
| SCHEMBL16063068 | 0.72 | ABCB1 (0.41) | ALDH1A1LMNASLC22A1SYNJ2 | |
| SCHEMBL17860796 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNAADRB2ADRB1ADRB3 | |
| SCHEMBL22799522 | 0.70 | NPC1 (0.42) | ALDH1A1LMNASLC22A1MAPK1KMT2A | |
| SCHEMBL16063064 | 0.70 | ABCB1 (0.37) | ALDH1A1LMNAADRB2ADRB1ADRB3 | |
| SCHEMBL6099509 | 0.68 | MAPT (0.42) | ALDH1A1LMNATDP1TSHRMAPK1 | |
| SCHEMBL8941400 | 0.68 | ALDH1A1 (0.41) | ALDH1A1LMNAADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212326-A4 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1212326-A1 | PYRROLO 2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN Pharmaceuticals, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001027114-A1 | PYRROLO[2,3-d]PYRIMIDINE NUCLEOSIDE ANALOGS | ICN PHARMACEUTICALS, INC. (US) | 2001-04-19 | — | — | WO | disclosed |