Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128388 | 0.88 | NQO1 (0.46) | NQO1TP53CYP3A4MEN1NPC1 | |
| SCHEMBL8561252 | 0.86 | NQO1 (0.33) | NQO1CYP11B1CYP11B2TUBB4ATUBB | |
| SCHEMBL1569511 | 0.85 | ESR1 (0.39) | NQO1CYP11B1CYP11B2TUBB4ATUBB | |
| SCHEMBL8405324 | 0.84 | AHR (0.44) | CYP3A4TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20703590 | 0.82 | MAPK1 (0.42) | NQO1TP53CYP3A4TUBB4ATUBB | |
| SCHEMBL8348426 | 0.81 | MAPK1 (0.37) | CYP3A4AHRMEN1KMT2ATSHR | |
| SCHEMBL9725912 | 0.81 | NQO1 (0.40) | NQO1TP53CYP3A4TUBB4ATUBB | |
| SCHEMBL15474940 | 0.81 | MAPK1 (0.40) | NPC1TSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL77754 | 0.81 | CA1 (0.39) | CYP3A4MEN1KMT2ATSHRTDP1 | |
| SCHEMBL28400785 | 0.81 | TSHR (0.47) | TP53TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431567-B2 | Substituted oxindole derivatives and their use as vasopressin and/or oxytocin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2013-04-30 | — | — | US | claimed |
| US-20090318406-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN AND/OR OXYTOCIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2009-12-24 | — | — | US | claimed |
| EP-2066657-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN AND/OR OXYTOCIN RECEPTOR LIGANDS | Abbott GmbH & Co. KG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008025735-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN AND/OR OXYTOCIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2008-03-06 | — | — | WO | claimed |
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | claimed |
| EP-1212331-B1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS INC (US) | 2004-04-21 | — | — | EP | claimed |
| US-6649595-B2 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD GENE THERAPEUTICS, INC. | 2003-11-18 | — | — | US | claimed |
| US-20020107189-A1 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD PHARMACEUTICALS, INC. | 2002-08-08 | — | — | US | claimed |
| EP-1212331-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2002-06-12 | — | — | EP | claimed |
| JP-2002508971-A | — | — | 2002-03-26 | — | — | JP | claimed |
| WO-2001014387-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2001-03-01 | — | — | WO | claimed |
| US-6187757-B1 | Regulation of biological events using novel compounds | ARIAD PHARMACEUTICALS, INC. | 2001-02-13 | — | — | US | claimed |
| EP-1045915-A2 | REGULATION OF BIOLOGICAL EVENTS USING MULTIMERIC CHIMERIC PROTEINS | ARIAD GENE THERAPEUTICS, INC. (US) | 2000-10-25 | — | — | EP | claimed |
| WO-1999036553-A2 | REGULATION OF BIOLOGICAL EVENTS USING MULTIMERIC CHIMERIC PROTEINS | ARIAD GENE THERAPEUTICS, INC. (US) | 1999-07-22 | — | — | WO | claimed |
| US-11678571-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | IDEMITSU KOSAN CO., LTD. (JP) | 2023-06-13 | — | — | US | disclosed |
| CN-110473989-B | Method for manufacturing organic light emitting element | 株式会社LG化学 | 2022-05-27 | — | — | CN | disclosed |
| US-20210376247-A1 | ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE | IDEMITSU KOSAN CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-4920110-A | PESTICIDES, MITICIDES, TICKS, NEMATOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0269859-A2 | Pyrazolotriazine compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678571-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | RPS17, RPS19, CDK17 | NQO1 457/4885TP53 4658/4885CYP3A4 1236/4885 |
| US-20090318406-A1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN AND/OR OXYTOCIN RECEPTOR LIGANDS | OXTR, AVPR2, AVPR1B | NQO1 2835/4885TP53 3280/4885CYP3A4 3668/4885 |
| US-20020107189-A1 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | FKBP2, FKBP14, FKBP4 | NQO1 4587/4885TP53 415/4885CYP3A4 2404/4885 |
| US-20210376247-A1 | ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE | RPS17, RPS19, CDK17 | NQO1 457/4885TP53 4658/4885CYP3A4 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.