Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KYNU | Q16719 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059278 | 1.00 | CTSK (0.54) | CTSKTACR1TYRCTRB1CTSS | |
| SCHEMBL1068617 | 0.91 | KYNU (0.62) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL18405554 | 0.91 | CTSL (0.56) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL1111097 | 0.91 | KYNU (0.62) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL1068619 | 0.91 | KYNU (0.62) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL376362 | 0.91 | PPARA (0.55) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL1111208 | 0.91 | PPARA (0.55) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL1111209 | 0.91 | PPARA (0.55) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL19659180 | 0.90 | HDAC1 (0.55) | CTSKTACR1CTRB1CTSSCTSL | |
| SCHEMBL18366279 | 0.90 | HDAC1 (0.55) | CTSKTACR1CTRB1CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195455-A | Herbicidal cinnolinium compounds | 先正达农作物保护股份公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2017165416-A1 | PROTECTED DERIVATIVES OF 2-AMINO-4-PHOSPHOBUTANOIC ACID | AGENUS INC. (US) | 2017-09-28 | — | — | WO | disclosed |
| US-6620820-B2 | Imidazole dione or one, thione derivatives as antitumor and antiinflammatory agents, also treats cardiovascular disease, nephropathies and retinopathies | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |
| US-20020119999-A1 | Novel inhibitors of bone reabsorption and antagonists of vitronectin receptors | HOECHST AKTIENGESELLSCHAFT | 2002-08-29 | — | — | US | disclosed |
| EP-0796855-B1 | Inhibitors of bone resorption and vitronectin receptor antagonists | HOECHST AG (DE) | 2002-02-06 | — | — | EP | disclosed |
| US-20010021708-A1 | Novel inhibitors of bone reabsorption and antagonists of vitronectin receptors | WEHNER VOLKMAR (DE) | 2001-09-13 | — | — | US | disclosed |
| US-6218415-B1 | THERAPY OF BONE REABSORPTION BY OSTEOCLASTS, TUMOR GROWTH AND TUMOR METASTASIS, INFLAMMATION, CARDIOVASCULAR DISEASE, NEPHROPATHIES AND RETINOPATHIES | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-04-17 | — | — | US | disclosed |
| EP-0796855-A1 | Inhibitors of bone resorption and vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021708-A1 | Novel inhibitors of bone reabsorption and antagonists of vitronectin receptors | ADGRF1, CALCR, SOST | CTSK 700/4885TACR1 35/4885TYR 4280/4885 |
| US-20020119999-A1 | Novel inhibitors of bone reabsorption and antagonists of vitronectin receptors | ADGRF1, CALCR, SOST | CTSK 700/4885TACR1 35/4885TYR 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.