Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219260 | 0.84 | ANO1 (0.42) | ANO1FFAR2KEAP1CYP2C9HDAC4 | |
| SCHEMBL7214349 | 0.75 | POLB (0.47) | ALDH1A1L3MBTL1ANO1LMNA | |
| SCHEMBL8650991 | 0.73 | CTSL (0.36) | ALDH1A1ANO1KEAP1LMNANFE2L2 | |
| SCHEMBL7220666 | 0.72 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1ANO1KEAP1LMNA | |
| SCHEMBL4620434 | 0.72 | SMN1; SMN2 (0.57) | ALDH1A1L3MBTL1NPSR1CYP2C9LMNA | |
| SCHEMBL4620431 | 0.72 | SMN1; SMN2 (0.57) | ALDH1A1L3MBTL1NPSR1CYP2C9LMNA | |
| SCHEMBL4620213 | 0.72 | SMN1; SMN2 (0.57) | ALDH1A1L3MBTL1NPSR1CYP2C9LMNA | |
| SCHEMBL8400798 | 0.71 | NPSR1 (0.43) | ALDH1A1NPSR1LMNA | |
| SCHEMBL8106282 | 0.70 | CTSK (0.40) | LMNA | |
| SCHEMBL8842237 | 0.69 | SMN1; SMN2 (0.48) | ALDH1A1L3MBTL1NPSR1ANO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504046-B1 | Cyclization of nitriles using acids, to form oxazolinone chemical intermediates such as 2-phenyl-4-isopropyl-4-methyl-1,3-oxazol-5-one, used as fungicides | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1092705-A1 | PROCESS FOR THE PREPARATION OF AMIDES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |