Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 2/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222409 | 0.89 | APP (0.39) | NTRK1KMT2ALMNAMAPTAPP | |
| SCHEMBL7217987 | 0.79 | CCNE2 (0.40) | MEN1KMT2ACCNE1CDK2CLK1 | |
| SCHEMBL7222469 | 0.78 | CDK2 (0.34) | MEN1KMT2ALMNAMAPTCDC7 | |
| SCHEMBL7222114 | 0.77 | CLK1 (0.49) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL7216330 | 0.76 | CD38 (0.40) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL7221634 | 0.68 | ATP1A1 (0.37) | MEN1KMT2ACDC7DBF4CCNE1 | |
| SCHEMBL7216137 | 0.67 | PDE9A (0.37) | KMT2AMAPTKDM4EGAAGRK6 | |
| SCHEMBL14134232 | 0.67 | CYP1A2 (0.48) | MEN1KMT2AMAPTTHRBALDH1A1 | |
| SCHEMBL7215632 | 0.65 | NPY5R (0.42) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL7215976 | 0.65 | GAA (0.44) | MEN1KMT2ALMNAMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |