Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GPR39 | O43194 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | GRK6 | P43250 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.34 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216137 | 0.89 | PDE9A (0.37) | KMT2AGRK6SLC6A2SLC6A4ATP1A1 | |
| SCHEMBL7222469 | 0.86 | CDK2 (0.34) | CCNE1CDK2MEN1KMT2ACCNT1 | |
| SCHEMBL7215977 | 0.79 | NTRK1 (0.39) | CCNE1CDK2MEN1KMT2ACLK1 | |
| SCHEMBL7215523 | 0.77 | SOS1 (0.37) | MEN1KMT2ASOS1GAA | |
| SCHEMBL7221634 | 0.75 | ATP1A1 (0.37) | CCNE1CDK2MEN1KMT2ACCNT1 | |
| SCHEMBL7222409 | 0.67 | APP (0.39) | KMT2AGPR39EGFR | |
| SCHEMBL7217985 | 0.67 | ATP1A1 (0.48) | CCNE2CCNE1CDK2MEN1KMT2A | |
| SCHEMBL14134232 | 0.66 | CYP1A2 (0.48) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7216330 | 0.65 | CD38 (0.40) | MEN1KMT2AGPR39CYP3A4CYP2C9 | |
| SCHEMBL14048209 | 0.63 | ALOX15 (0.45) | CDK2MEN1KMT2ACCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |