Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | GPR39 | O43194 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215977 | 0.89 | NTRK1 (0.39) | APPNTRK1LMNAMAPTKMT2A | |
| SCHEMBL7216330 | 0.85 | CD38 (0.40) | LMNAGPR39MAPTKMT2A | |
| SCHEMBL7216137 | 0.79 | PDE9A (0.37) | PDE5AMAPTHSD17B10KMT2A | |
| SCHEMBL7221634 | 0.78 | ATP1A1 (0.37) | KMT2ACDC7DBF4 | |
| SCHEMBL7215632 | 0.77 | NPY5R (0.42) | LMNATYMSPDE5AMAPTFABP4 | |
| SCHEMBL7215523 | 0.73 | SOS1 (0.37) | LMNAMAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL7215731 | 0.73 | KMT2A (0.35) | LMNAMAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL7222469 | 0.68 | CDK2 (0.34) | LMNAMAPTKMT2APOLBCDC7 | |
| SCHEMBL7217987 | 0.67 | CCNE2 (0.40) | GPR39EGFRKMT2A | |
| SCHEMBL3359902 | 0.67 | MAPT (0.45) | LMNAMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |