Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 6/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE8A | O60658 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.34 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.34 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.34 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.34 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.34 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.34 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7217987 | 0.89 | CCNE2 (0.40) | GRK6ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL7221634 | 0.86 | ATP1A1 (0.37) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7215523 | 0.85 | SOS1 (0.37) | MAPTNPSR1GAAKMT2AAR | |
| SCHEMBL7222409 | 0.79 | APP (0.39) | PDE5AMAPTKMT2AHSD17B10 | |
| SCHEMBL7215731 | 0.77 | KMT2A (0.35) | MAPTNPSR1KDM4EGAAKMT2A | |
| SCHEMBL7222469 | 0.75 | CDK2 (0.34) | SLC6A2SLC6A4MAPTHPGDNPSR1 | |
| SCHEMBL7216330 | 0.73 | CD38 (0.40) | PDE9AMAPTCYP3A4CYP2C9KMT2A | |
| SCHEMBL7215977 | 0.67 | NTRK1 (0.39) | GRK6MAPTHPGDKDM4EGAA | |
| SCHEMBL7216134 | 0.67 | ATP1A1 (0.48) | PDE9APDE1BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL28676692 | 0.63 | GAA (0.61) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596739-B2 | Anticarcinogenic agents, cardiovascular disorders and antiinflammatory agents | THE PROCTER & GAMBLE COMPANY | 2003-07-22 | — | — | US | claimed |