Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 11/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073390 | 0.78 | LTA4H (0.41) | IDO1AGXT | |
| SCHEMBL12783776 | 0.78 | IDO1 (0.35) | IDO1AGXTPREP | |
| SCHEMBL5221804 | 0.78 | IDO1 (0.35) | IDO1AGXTPREP | |
| SCHEMBL12002628 | 0.78 | IDO1 (0.46) | IDO1AGXTPREP | |
| SCHEMBL9033464 | 0.76 | CYP17A1 (0.46) | — | |
| SCHEMBL6212378 | 0.74 | WNT3A (0.34) | WNT3AS1PR1S1PR3GPR119CHRM4 | |
| SCHEMBL6212376 | 0.74 | WNT3A (0.34) | WNT3AS1PR1S1PR3GPR119 | |
| SCHEMBL7216378 | 0.74 | WNT3A (0.33) | WNT3AIDO1AGXT | |
| SCHEMBL15489965 | 0.73 | TDP1 (0.37) | AGXT | |
| SCHEMBL581041 | 0.73 | LOXL2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599918-B2 | Inhibit Factor Xa Factor IIa (thrombin) | AVENTIS PHARMACEUTICALS INC. | 2003-07-29 | — | — | US | disclosed |