Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 9/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212657 | 0.75 | EP300 (0.35) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL6212659 | 0.75 | EP300 (0.35) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL13478010 | 0.75 | WNT3A (0.40) | WNT3AHDAC4DHODHEP300F2 | |
| SCHEMBL28129052 | 0.74 | DUT (0.33) | — | |
| SCHEMBL7216290 | 0.74 | WNT3A (0.36) | WNT3AIDO1AGXT | |
| SCHEMBL13637169 | 0.73 | RAB9A (0.44) | WNT3AHDAC4DHODHPRMT5WDR77 | |
| SCHEMBL17440111 | 0.72 | NAAA (0.42) | HDAC4 | |
| SCHEMBL1315036 | 0.72 | IDO1 (0.46) | IDO1AGXT | |
| SCHEMBL5221804 | 0.72 | IDO1 (0.35) | IDO1AGXT | |
| SCHEMBL12002628 | 0.72 | IDO1 (0.46) | IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599918-B2 | Inhibit Factor Xa Factor IIa (thrombin) | AVENTIS PHARMACEUTICALS INC. | 2003-07-29 | — | — | US | disclosed |