Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216128 | 0.91 | PARP10 (0.44) | PARP10PARP14MEN1KMT2AL3MBTL1 | |
| SCHEMBL7217018 | 0.91 | PARP14 (0.36) | PARP10PARP14L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL7215840 | 0.89 | PPARD (0.37) | PARP10PARP14KMT2AL3MBTL1KDM4E | |
| SCHEMBL7218231 | 0.87 | MAPT (0.34) | PARP10PARP14MEN1KMT2AL3MBTL1 | |
| SCHEMBL7216783 | 0.86 | PPARD (0.35) | PARP10PARP14MEN1KMT2AL3MBTL1 | |
| SCHEMBL7218103 | 0.86 | NR4A2 (0.49) | MEN1KMT2AALKBH1NPC1RAB9A | |
| SCHEMBL7218091 | 0.83 | PARP10 (0.37) | PARP10PARP14MEN1KMT2AL3MBTL1 | |
| SCHEMBL7216431 | 0.82 | MRGPRX4 (0.50) | ALKBH1NPC1RAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL7222714 | 0.81 | FFAR4 (0.32) | — | |
| SCHEMBL7216417 | 0.81 | PPARD (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |