Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215840 | 0.95 | PPARD (0.37) | PPARDKMT2APARP14PARP10KDM4E | |
| SCHEMBL7218231 | 0.94 | MAPT (0.34) | PPARDKMT2AALDH1A1PTK2BLMNA | |
| SCHEMBL7218151 | 0.91 | PPARD (0.34) | PPARDKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7217018 | 0.89 | PARP14 (0.36) | ALDH1A1LMNAMAPTPARP14PARP10 | |
| SCHEMBL7216417 | 0.86 | PPARD (0.42) | PPARDKMT2AALOX5PTGESPPARG | |
| SCHEMBL7222714 | 0.86 | FFAR4 (0.32) | PTGDR2FFAR1 | |
| SCHEMBL7216335 | 0.86 | PARP10 (0.45) | KMT2AALDH1A1MAPTPARP14PARP10 | |
| SCHEMBL7218190 | 0.86 | PPARD (0.43) | PPARDKMT2AMAPTALOX5PTGES | |
| SCHEMBL7215961 | 0.85 | HRH3 (0.39) | KMT2ALMNAKDM4ESMN1; SMN2ALOX5 | |
| SCHEMBL7218226 | 0.85 | PARP14 (0.34) | PPARDKMT2ALMNAMAPTPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |